Author(s): Akshara, Krupanidhi A.M, Ashok R .Chanchi, Akshaykumar K and Yashaswini.T
Depression is the leading cause of disability and the fourth leading contributor to the global burden of disease in 2000. Today, depression is already the second cause in the age category 15-44 years for both sexes combined. The present study was designed to evaluate the anti‐depressant activity of ethanol extract of the leaves of Drypetusroxburgii belonging to family Euphorbiaceae by using actophotometer and forced swimming test (FST) in Swiss albino mice. The albino mice were treated with ethanol extract at a dose of 500mg/kg orally and behaviour was observed on actophotometer and FST. The results showed that ethanol extract at a dose of 500mg/kg of the leaves of Drypetusroxburgii has anti-depressant activity.
Keywords: Drypetusroxburgii, Forced swim test, anti‐depressant, actophotometer