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IN VITRO ANTIOXIDANT ACTIVITY OF HYDROALCOHOLIC EXTRACT OF DEVA VATI TABLETS: AN AYURVEDIC FORMULATION

Author(s): Anjali Nair G, K.T Manisenthil Kumar, J.Saravanan

ABSTRACT

The generation of free radical is responsible for the development of several aging-related diseases including cancer, cardiovascular disorder, diabetes, neurodegenerative disorders. The objective of the present study was to evaluate the in vitro antioxidant potential of a hydro-alcoholic extract of deva vati tablet (HEDV). The formulation was standardized pharmaceutically and microbiologically. In vitro antioxidant study such as total phenolic content, DPPH assay and ABTS assay were performed. Quercetin was taken as the standard for antioxidant activity. The total phenolic content of HEDV was found to be 8.41 µg. The antioxidant activity was estimated by IC50 value and the values are (1.97 μg/ml (DPPH radical scavenging assay) and 0.660μg/ml.(ABTS radical scavenging assay) Hence, the extract showed significant in vitro antioxidant activity by terminating the actions of free radicals.

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